One new unusual sesterterpenoid and four new sesquiterpene dimers from Inula britannica

One new unusual sesterterpenoid ( 1 ), four new sesquiterpene dimers ( 2–5 ) together with nine known sesquiterpenes ( 6–14 ) were isolated from the aerial parts of Inula britannica . The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HR-ESIMS and 2D-NM...

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Published inRSC advances Vol. 5; no. 3; pp. 1979 - 1982
Main Authors Zhang, Xu-Feng, Ren, Jie, Cheng, Xiang-Rong, Jin, Hui-Zi, Zhang, Wei-Dong
Format Journal Article
LanguageEnglish
Published 01.01.2015
Subjects
Aerials
Dimers
Macrophages
Spectroscopic analysis
Spectroscopy
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Summary:One new unusual sesterterpenoid ( 1 ), four new sesquiterpene dimers ( 2–5 ) together with nine known sesquiterpenes ( 6–14 ) were isolated from the aerial parts of Inula britannica . The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HR-ESIMS and 2D-NMR spectroscopic methods. In addition, compounds 1–8 and 10–11 were tested for their inhibitory effects against LPS-induced NO production in RAW264.7 macrophages.
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ISSN:2046-2069
2046-2069
DOI:10.1039/C4RA11171K