Prevalence of serum antibodies to toxic-shock-syndrome-toxin-1 and to staphylococcal enterotoxins A, B and C in West-Germany

Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and...

Full description

Saved in:
Bibliographic Details
Published inZentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Vol. 270; no. 1-2; p. 110
Main Authors Schröder, E, Kunstmann, G, Hasbach, H, Pulverer, G
Format Journal Article
LanguageEnglish
Published Germany 01.11.1988
Subjects
Adult
Antibodies, Bacterial - analysis
Bacterial Toxins
Blood Donors
Enterotoxins - immunology
Enzyme-Linked Immunosorbent Assay
Germany, West
Humans
Infant
Middle Aged
Shock, Septic - epidemiology
Staphylococcus aureus - immunology
Superantigens
Germany, West
Online AccessGet more information

Cover

More Information
Summary:Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and 90% to enterotoxin B and TSST-1, which is very similar to the prevalence of TSST-1 antibodies among USA-residents. The "protective" titer of TSST-1-antibodies can be estimated to be 1:100 in the test system used by comparison with anti-TSST-1-titers in five acute phase sera from confirmed menstrual TSS cases.
ISSN:0176-6724
DOI:10.1016/S0176-6724(88)80146-9