The Varieties of Auditory Neuropathy
Auditory neuropathy (AN) was initially described as impairment of auditory neural function, with preserved cochlear hair cell function. In this report, 67 patients with audiological and neurophysiological criteria for hearing loss due to auditory neuropathy are described. Reviewing this large body o...
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Published in | Journal of basic and clinical physiology and pharmacology Vol. 11; no. 3; pp. 215 - 230 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Germany
De Gruyter
2000
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Subjects | |
Online Access | Get full text |
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Summary: | Auditory neuropathy (AN) was initially described as impairment of auditory neural function, with preserved cochlear hair cell function. In this report, 67 patients with audiological and neurophysiological criteria for hearing loss due to auditory neuropathy are described. Reviewing this large body of patients, AN appears to consist of a number of varieties, with different etiologies and sites affected. All varieties share a relatively spared receptor function, and an impaired neural response, with diminished ability to follow fast temporal changes in the stimulus, but different varieties in this general scheme can be distinguished. Analyses of the clinical features indicate that auditory neuropathies vary in several measures including age of onset, presence of peripheral neuropathy, etiology, and behavioral and physiological measures of auditory function. The sites affected along the peripheral auditory pathway may include dysfunction of the outer hair cells, the synapse between hair cell and auditory nerve, and the auditory nerve fibers, with myelin as well as axonal impairments contributing to the disorder. |
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Bibliography: | ark:/67375/QT4-N2H1H32R-R jbcpp.2000.11.3.215.pdf istex:22B955F5E61FD520F0D42C5019EA9C827DADB319 ArticleID:JBCPP.2000.11.3.215 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0792-6855 2191-0286 |
DOI: | 10.1515/JBCPP.2000.11.3.215 |