Deactivations during the numerical processing

• Published in: Chinese science bulletin Vol. 52; no. 13; pp. 1807 - 1812
• Main Authors: Feng, HongBo, Zhang, Ye, Tang, YiYuan, Jin, Jing, Dong, Feng, Feng, ShiGang, Zhang, WuTian
• Format: Journal Article
• Language: English
• Published: State Key Laboratory of Brain and Cognitive Science, Chinese Academy of Sciences, Beijing 100101, China 01.07.2007; Institute of Neuroinformatics, Dalian University of Technology, Dalian 116024, China%Institute of Neuroinformatics, Dalian University of Technology, Dalian 116024, China
• Subjects: 休眠状态; 数值叠加法; 灭活方法; 生物活性; fMRI; resting state; numerical addition; insula; deactivation
• ISSN: 1001-6538; 1861-9541
• DOI: 10.1007/s11434-007-0256-3

Deactivation has been encountered frequently in functional brain imaging researches. However, the deactivations during the numerical processing have not been reported yet. In this study, the functional magnetic resonance imaging （fMRI） was employed to investigate the pattern of the deactivation in the brain of 15 healthy subjects during the numerical addition task. Analyses revealed significant deacti- vations in several brain regions, including the posterior cingulate, precuneus, anterior cingulate and prefrontal cortex. Especially, we found notable deactivation in bilateral insula. Accounting for the cognitive functions of these regions participating in a combinated way, we discuss their contributions in sustaining the brain activity during conscious resting state, and indicate that the insula is an important area of gathering auditory information from the external world.