A spectrophotometric method for the estimation of the carcinostatic agent 6-chrysenamine (E.O.R.T.C. II6) in biological fluids and tissues

An analytical method for the estimation of 6-chrysenamine (E.O.R.T.C. 116) in biological fluids and tissues is described. Blood and tumor levels were evaluated after a single and a subchronic treatment with 6-chrysenamine administered by different routes in (C 3 H × O 20 ) F 1 mice bearing spontaneo...

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Bibliographic Details
Published inEuropean journal of cancer Vol. 9; no. 8; pp. 591 - 595
Main Authors Franchi, G., Forgione, A., Filippeschi, S., Csetényi, J., Garattini, S.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.01.1973
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Summary:An analytical method for the estimation of 6-chrysenamine (E.O.R.T.C. 116) in biological fluids and tissues is described. Blood and tumor levels were evaluated after a single and a subchronic treatment with 6-chrysenamine administered by different routes in (C 3 H × O 20 ) F 1 mice bearing spontaneous mammary tumor. The results obtained are discussed in terms of their therapeutical significance for experimental chemotherapy.
ISSN:0014-2964
DOI:10.1016/0014-2964(73)90150-3