Zyderm collagen: Implantation technics

• Published in: Journal of the American Academy of Dermatology Vol. 10; no. 2; pp. 273 - 278
• Main Authors: Tromovitch, Theodore A., Stegman, Samuel J., Glogau, Richard G.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.02.1984; Elsevier
• Subjects: Biological and medical sciences; Cicatrix - therapy; Collagen - administration & dosage; Collagen - therapeutic use; Face; Humans; Injections, Intradermal; Lip; Medical sciences; Needles; Skin; Skin plastic surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Plastic surgery; Skin disease; Injection; Technique; Collagen
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/S0190-9622(84)70036-3

This paper describes in detail the injection technics for Zyderm collagen, purified bovine collagen (EPC), presently used by us. Because we were clinical investigators, we have used the material for longer than 6 years. The paper outlines our initial technics, some of which were successful and some, not successful. Equipment, patient positioning, technics for estimating whether or not EPC will work, syringe and needle positioning, and how best to judge whether or not the implant is being placed in the dermis are discussed. Each indication for EPC and each area where EPC is effective are addressed individually, with special emphasis on the precise technic that produces the best and longest-lasting results. Because we feel that injection technic is critical for safety and efficacy, this detailed description of the technic and how it was derived is submitted for others to share.