Highly enantioselective fluorescent recognition of α-amino acid derivatives

Graphic Bisbinaphthyl-based macrocycles are found to carry out enantioselective fluorescent recognition of α-amino acid derivatives. It is observed that one enantiomer of a N-protected phenyl glycine can increase the fluorescence intensity of the binaphthyl fluorophores by over 4-fold but the other...

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Bibliographic Details
Published inTetrahedron letters Vol. 45; no. 1; pp. 103 - 106
Main Authors Lin, Jing, Li, Zi-Bo, Zhang, Hui-Chang, Pu, Lin
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 2004
Subjects
amino acids
binaphthyl macrocycles
enantioselective
fluorescent sensors
binaphthyl macrocycles
fluorescent sensors
amino acids
enantioselective
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Summary:Graphic Bisbinaphthyl-based macrocycles are found to carry out enantioselective fluorescent recognition of α-amino acid derivatives. It is observed that one enantiomer of a N-protected phenyl glycine can increase the fluorescence intensity of the binaphthyl fluorophores by over 4-fold but the other enantiomer does not cause much fluorescence enhancement. This highly enantioselective fluorescent response makes the binaphthyl macrocycles practically useful for the enantioselective fluorescent recognition of the amino acid substrate.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2003.10.116