Etoposide-related myocardial infarction

The occurrence of a myocardial infarction is reported after chemotherapy containing etoposide, in a man with no risk factors for coronary heart disease. Possible causal mechanisms are discussed.

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Bibliographic Details
Published inClinical oncology (Royal College of Radiologists (Great Britain)) Vol. 7; no. 2; p. 135
Main Authors Airey, C.L., Dodwell, D.J., Joffe, J.K., Jones, W.G.
Format Journal Article Conference Proceeding
LanguageEnglish
Published Amsterdam Elsevier Ltd 1995
Elsevier
Subjects
Adult
Biological and medical sciences
Drug toxicity and drugs side effects treatment
Etoposide
Etoposide - adverse effects
Germ cell tumour
Humans
Male
Medical sciences
Myocardial infarction
Myocardial Infarction - chemically induced
Pharmacology. Drug treatments
Seminoma - drug therapy
Teratoma - drug therapy
Testicular Neoplasms - drug therapy
Toxicity: cardiovascular system
Myocardial infarction
Etoposide
Germ cell tumour
Human
Antineoplastic agent
DNA topoisomerase (ATP-hydrolysing)
Infarct
Enzyme
Toxicity
Enzyme inhibitor
Cardiovascular disease
Malignant tumor
Malignant teratoma
Coronary heart disease
Myocardial disease
Case study
Seminoma
Chemotherapy
Isomerases
Treatment
Young adult
Myocardium
Complication
Antimitotic
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Summary:The occurrence of a myocardial infarction is reported after chemotherapy containing etoposide, in a man with no risk factors for coronary heart disease. Possible causal mechanisms are discussed.
ISSN:0936-6555
1433-2981
DOI:10.1016/S0936-6555(05)80819-2