A practical synthesis of 3( S)-methyl-heptanoic acid from ( S)-citronellol

Chiral 3-methyl-heptanoic acid is readily accessible by functional group manipulation of optically active citronellol. In principle, this approach is general and could be applied to the synthesis of chiral 3-methyl-alkanoic acids seven carbon atoms in length and longer. Graphic

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Bibliographic Details
Published inTetrahedron: asymmetry Vol. 7; no. 2; pp. 435 - 442
Main Authors Breitenbach, Ralph, Chiu, Charles K.-F., Massett, Stephen S., Meltz, Morgan, Murtiashaw, C.William, Pezzullo, Susan L., Staigers, Thomas
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 01.02.1996
Elsevier
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
Physical Sciences
Science & Technology
ALCOHOLS
REAGENTS
PHEROMONE
ASYMMETRIC CONJUGATE ADDITION
ALKANOIC ACIDS
ISOMERIZATION
OXIRANES
DERIVATIVES
AMIDES
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Summary:Chiral 3-methyl-heptanoic acid is readily accessible by functional group manipulation of optically active citronellol. In principle, this approach is general and could be applied to the synthesis of chiral 3-methyl-alkanoic acids seven carbon atoms in length and longer. Graphic
ISSN:0957-4166
1362-511X
DOI:10.1016/0957-4166(96)00026-2