Bridging anatomical gaps between brain and immune system

It is increasingly clear that the central nervous system (CNS) relies significantly on both adaptive and innate immune cells for its repair and lifelong maintenance. These interactions hold profound implications for brain aging and neurodegeneration. Recent work by Smyth et al. describes newfound an...

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Bibliographic Details
Published inTrends in immunology Vol. 45; no. 5; pp. 318 - 319
Main Authors Castellani, Giulia, Peralta Ramos, Javier María, Schwartz, Michal
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.05.2024
Subjects
Adaptive Immunity
Aging - immunology
Animals
Brain - immunology
Dura Mater - immunology
Humans
Immune System - immunology
Immunity, Innate
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Summary:It is increasingly clear that the central nervous system (CNS) relies significantly on both adaptive and innate immune cells for its repair and lifelong maintenance. These interactions hold profound implications for brain aging and neurodegeneration. Recent work by Smyth et al. describes newfound anatomical connections between the brain and dura mater, which they named the arachnoid cuff exit points. It is increasingly clear that the central nervous system (CNS) relies significantly on both adaptive and innate immune cells for its repair and lifelong maintenance. These interactions hold profound implications for brain aging and neurodegeneration. Recent work by Smyth et al. describes newfound anatomical connections between the brain and dura mater, which they named the arachnoid cuff exit points.
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ISSN:1471-4906
1471-4981
DOI:10.1016/j.it.2024.04.006