Neuropeptides, nerve growth factor, and mucosal immunity
Since the discovery more than 20 years ago that IgA in its secretory form of dimeric IgA covalently linked with the glycoprotein, secretory component (SC), the predominant immunoglobulin in external secretions, the emphasis has been on this molecule as a prime mediator of mucosal immunity. While the...
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Published in | Brain, behavior, and immunity Vol. 2; no. 4; pp. 311 - 317 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Inc
01.12.1988
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Subjects | |
Online Access | Get full text |
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Summary: | Since the discovery more than 20 years ago that IgA in its secretory form of dimeric IgA covalently linked with the glycoprotein, secretory component (SC), the predominant immunoglobulin in external secretions, the emphasis has been on this molecule as a prime mediator of mucosal immunity. While there is no doubt that IgA is an important effector molecule, there is increasing evidence that often it may be only a marker of an effective mucosal response and that other mechanisms are involved in inducing mucosal resistance. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0889-1591 1090-2139 |
DOI: | 10.1016/0889-1591(88)90033-5 |