Syringaldehyde isolated from Abutilon indicum Linn. leaves exhibits broad spectrum anti-microbial activity

Abutilon indicum Linn. (AI) is used in ayurvedic system and has shown potential to treat microbial infections. In the present study syringaldehyde was reported for the first time from the leaves of AI ethyl acetate extract and quantified by HPTLC analysis. Further, syringaldehyde showed significant...

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Bibliographic Details
Published inMaterials today : proceedings Vol. 50; pp. 335 - 339
Main Authors Anjum Musthafa, Shazia, Dabdoub, Waleed, Sadiq, Muhammad, Munuswamy-Ramanujam, Ganesh
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.01.2022
Subjects
Abutilon indicum Linn
Antimicrobial activity
Ayurveda
Hepato protective
Malvaceae
PBS
DPPH 2
Malvaceae
Ayurveda
Antimicrobial activity
DMSO
KP
AI
Hepato protective
Abutilon indicum Linn
BS
NMR
EA
ABTS
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Summary:Abutilon indicum Linn. (AI) is used in ayurvedic system and has shown potential to treat microbial infections. In the present study syringaldehyde was reported for the first time from the leaves of AI ethyl acetate extract and quantified by HPTLC analysis. Further, syringaldehyde showed significant broad spectrum anti-bacterial activity against Bacillus subtilis (BS) andKlebsiella pneumonia (KP). CLSM analysis also indicated at the ability of the molecule to inhibit biofilm formation in fungus Aspergillus fumigatus indicating its potent anti-fungal activity. Overall the molecule has potential to be used as anti-microbial compound with wide application.
ISSN:2214-7853
2214-7853
DOI:10.1016/j.matpr.2021.08.062