A Case Report of Cronkhite-Canada Syndrome Successfully Remitted by Surgical Treatment

• Published in: Nippon Shokaki Geka Gakkai zasshi Vol. 40; no. 2; pp. 227 - 232
• Main Authors: Toizumi, Atsushi, Kabeshima, Yasuo, Izawa, Naoko, Yano, Kazuhito, Tamura, Yoichiro, Kaneko, Kotaro, Kageyama, Takahisa
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society of Gastroenterological Surgery 2007
• Subjects: Cronkhite-Canada syndrome; protein-losing enteropathy; surgical treatment
• ISSN: 0386-9768; 1348-9372
• DOI: 10.5833/jjgs.40.227

A Japanese woman in her 50s admitted for abdominal pain, anorexia and dysgeusia from December 2002 gradually showed finger chromatosis, nail plate atrophy, glossitis, and a 10kg weight loss in two months. We diagnosed the case as Cronkhite-Canada syndrome. Symptoms were ameliorated by conservative treatment. Readmission was required in November 2004.Though we performed conservative treatment, bowel obstruction occurred. Colonography showed multiple granular tubercles in the ascending colon and ileal obstruction. We conducted laparoscopic ileocecal resection. Pathological diagnosis showed an inflammatory polyp of about 25cm at terminal ileum and advanced edema. The postoperative course was good and blood albumin improved to 4.4g/dl, body weight increased and diarrhea, chromatosis, depilation, and nail plate atrophy were resolved in 2POM. We concluded that surgery is a choice of the treatment in patients who do not respond to conservative therapy.