A case of adult Still's disease occurred during pregnancy

• Published in: Japanese Journal of Clinical Immunology Vol. 14; no. 6; pp. 633 - 638
• Main Authors: Izuhara, Kenji, Takeda, Hiroko, Niiro, Hiroaki, Motomura, Seiji, Shindou, Masafumi, Kitajima, Masahiro, Ishikawa, Haruhide, Tokunaga, Michiko
• Format: Journal Article
• Language: English
• Published: The Japan Society for Clinical Immunology 1991
• Subjects: adult Still's disease; aspirin; naproxen; pregnancy
• ISSN: 0911-4300; 1349-7413
• DOI: 10.2177/jsci.14.633

A case of adult Still's disease occurred during pregnancy was reported. A 30-year-old woman in the 18th week of pregnancy was admitted because of fever and polyarthralgia. She had an episode of unknown fever suggesting adult Still's disease at the age of 19. Physical examinations revealed lymphadenopathy, hepatosplenomegaly and swelling of many joints in decreased motion. A macular rash which had appeared with fever was present on the legs. Laboratory data revealed rapid ESR, neutrophilia, mild liver dysfunction, positive CRP and elevation of serum ferritin. A diagnosis of probable adult Still's disease was made because other febrile diseases were denied. After admission, she was treated with aspirin, resulted in exacervation of liver dysfunction, but was much improved with naproxen. Intrauterine growth retardation was suggested at one time, but at the 38th week of gestation, she delivered a healthy baby with no problems and no recurrence has been occurred till now. Six cases of adult Still's disease occurred during pregnancy are reported including the present case and discussions were made on such cases in the present paper.