Comparison of the effect of aerosols of saline and mineral water on the tracheal epithelium
Ultrastructure of the airway epithelium and character of glycoconjugates produced by secretory cells were studied after 10-min inhalations of saline and mineral water aerosols. Methods of electron microscopy and conventional and lectin histochemistry were used. The target cells for the function of b...
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Published in | Acta veterinaria Brno Vol. 72; no. 2; pp. 151 - 156 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
01.06.2003
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Subjects | |
Online Access | Get full text |
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Summary: | Ultrastructure of the airway epithelium and character of glycoconjugates produced by secretory cells were studied after 10-min inhalations of saline and mineral water aerosols. Methods of electron microscopy and conventional and lectin histochemistry were used. The target cells for the function of both aerosols were the goblet cells. These cells were overstimulated and the mechanism of mucus evacuation was accelerated. The exhausted goblet mostly took part in further secretory cycles. The cells not entirely filled with secretory granules prevailed in the epithelium. Massive differentiation of new secretory elements caused changes in the secretory cells' distribution. Of the two aerosols, only mineral water induced significant changes in the composition of glycoconjugates in the secretion of goblet cells. The percentage of altered cilia was significantly lower after saline water inhalation than after mineral water inhalation. From the morphological point of view, administration of saline aerosol is less harmful compared with that of mineral water. |
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Bibliography: | L74 2003000899 |
ISSN: | 0001-7213 1801-7576 |
DOI: | 10.2754/avb200372020151 |