Comparison of the effect of aerosols of saline and mineral water on the tracheal epithelium

Ultrastructure of the airway epithelium and character of glycoconjugates produced by secretory cells were studied after 10-min inhalations of saline and mineral water aerosols. Methods of electron microscopy and conventional and lectin histochemistry were used. The target cells for the function of b...

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Published inActa veterinaria Brno Vol. 72; no. 2; pp. 151 - 156
Main Author Konradova, V., Vajner, L., Uhlik, J., Zocova, J. (Karlova Univ., Prague (Czech Republic). Ustav Histologie a Embryologie)
Format Journal Article
LanguageEnglish
Published 01.06.2003
Subjects
ACIDE
ACIDS
AEROSOLES
AEROSOLS
AGUA MINERAL
AGUA SALINA
ANIMAL TISSUES
AÉROSOL
CELLS
CELLULE
CELULAS
CHEMICAL COMPOSITION
COMPOSICIÓN QUIMICA
COMPOSITION CHIMIQUE
CONEJO (ORYCTOLAGUS)
DAMAGE
DAÑOS
DÉGÂT
EAU MINÉRALE
EAU SALINE
EPITELIO
EPITHELIUM
EXOCRINE GLANDS
GLANDE EXOCRINE
GLÁNDULAS EXOCRINAS
LAPIN (ORYCTOLAGUS)
LECTINAS
LECTINE
LECTINS
MICROSCOPIA
MICROSCOPIE
MICROSCOPY
MINERAL WATERS
MOCO
MUCUS
RABBITS
REGENERACIÓN
REGENERATION
RÉGÉNÉRATION
SALINE WATER
SECRECIÓN
SECRETION
SÉCRÉTION
TEJIDOS ANIMALES
TISSU ANIMAL
TRACHEA
TRACHÉE
TRÁQUEA
ULTAESTRUCTURA
ULTRASTRUCTURE
ÁCIDOS
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Summary:Ultrastructure of the airway epithelium and character of glycoconjugates produced by secretory cells were studied after 10-min inhalations of saline and mineral water aerosols. Methods of electron microscopy and conventional and lectin histochemistry were used. The target cells for the function of both aerosols were the goblet cells. These cells were overstimulated and the mechanism of mucus evacuation was accelerated. The exhausted goblet mostly took part in further secretory cycles. The cells not entirely filled with secretory granules prevailed in the epithelium. Massive differentiation of new secretory elements caused changes in the secretory cells' distribution. Of the two aerosols, only mineral water induced significant changes in the composition of glycoconjugates in the secretion of goblet cells. The percentage of altered cilia was significantly lower after saline water inhalation than after mineral water inhalation. From the morphological point of view, administration of saline aerosol is less harmful compared with that of mineral water.
Bibliography:L74
2003000899
ISSN:0001-7213
1801-7576
DOI:10.2754/avb200372020151