Late‐onset and congenital hearing loss detected using AABR due to congenital cytomegalovirus infection that improved with valganciclovir

• Published in: Congenital anomalies Vol. 63; no. 2; pp. 40 - 43
• Main Authors: Morimoto, Chihiro, Nishikubo, Toshiya, Nishimura, Tadashi, Onishi, Tomoko, Takeyama, Masahiro, Uchida, Yumiko, Otsuka, Shintaro, Yamanaka, Toshiaki, Kitahara, Tadashi
• Format: Journal Article
• Language: English
• Published: Kyoto, Japan John Wiley & Sons Australia, Ltd 01.03.2023; Wiley Subscription Services, Inc
• Subjects: automated ABR; Brain stem; congenital cytomegalovirus infection; congenital hearing loss; Cytomegalovirus; Cytomegalovirus Infections - congenital; Cytomegalovirus Infections - diagnosis; Disabilities; Evoked Potentials, Auditory, Brain Stem; Hearing; hearing improvement; Hearing loss; Hearing Loss, Sensorineural - congenital; Hearing Loss, Sensorineural - diagnosis; Humans; Infant, Newborn; Infections; late‐onset hearing loss; Neonatal Screening - adverse effects; Neonates; Neurodevelopmental disorders; Valganciclovir; automated ABR; hearing improvement; congenital cytomegalovirus infection; congenital hearing loss; late-onset hearing loss
• ISSN: 0914-3505; 1741-4520
• DOI: 10.1111/cga.12501

Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection and is the leading non‐genetic cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities. Auto auditory brainstem response (AABR) is a simple hearing test and used for the purpose of neonatal hearing screening, but can use it for early detection hard of hearing within the study age of the model. We experienced two case of asymptomatic CMV infection in which congenital and late‐onset hearing loss were diagnosed early with AABR, and hearing loss improved with valganciclovir.