Asymmetric organotellurides as potent antioxidants and building blocks of protein conjugates

New asymmetric organotellurides exhibiting good antioxidant properties in vitro and in cell culture can be attached to human serum albumin.

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Bibliographic Details
Published inOrganic & biomolecular chemistry Vol. 3; no. 6; pp. 975 - 980
Main Authors Pariagh, S, Tasker, KM, Fry, FH, Holme, AL, Collins, CA, Okarter, N, Gutowski, N, Jacob, C
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 21.03.2005
Subjects
Antioxidants - chemical synthesis
Antioxidants - pharmacology
Cell Survival - drug effects
Chemistry
Chemistry, Organic
Glutathione Peroxidase - metabolism
Humans
Kinetics
Lung Neoplasms - drug therapy
Lung Neoplasms - metabolism
Metallothionein - metabolism
Organometallic Compounds - chemical synthesis
Organometallic Compounds - pharmacology
Peroxides - chemistry
Phenols - chemistry
Physical Sciences
Science & Technology
Serum Albumin - metabolism
Sulfhydryl Compounds - chemistry
Tellurium - chemistry
Tellurium - pharmacology
Zinc - metabolism
HIGH CATALYTIC EFFICIENCY
METALLOTHIONEIN
GLUTATHIONE-PEROXIDASE
EBSELEN
LABEL
SULFUR
CANCER
SELENIUM
ZINC
TRANSFERASE
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Summary:New asymmetric organotellurides exhibiting good antioxidant properties in vitro and in cell culture can be attached to human serum albumin.
ISSN:1477-0520
1477-0539
DOI:10.1039/b500409h