Buerger's disease in the modern era

In an effort to determine the current incidence and clinical course of Buerger's disease, we reviewed the records of over 700 patients with small artery disease who were evaluated at Oregon Health Sciences University during a 15 year period. We identified 26 patients who met rigid criteria for...

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Published inThe American journal of surgery Vol. 154; no. 1; pp. 123 - 129
Main Authors Mills, Joseph L., Taylor, Lloyd M., Porter, John M.
Format Journal Article Conference Proceeding
LanguageEnglish
Published New York, NY Elsevier Inc 01.07.1987
Elsevier
Subjects
Adolescent
Adult
Amputation
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Combined Modality Therapy
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Female
Femoral Artery - diagnostic imaging
Fingers - blood supply
Follow-Up Studies
Histocompatibility Testing
Humans
Leg - blood supply
Leg - surgery
Male
Medical sciences
Middle Aged
Prognosis
Radiography
Retrospective Studies
Smoking
Thromboangiitis Obliterans - diagnosis
Thromboangiitis Obliterans - pathology
Thromboangiitis Obliterans - surgery
Human
Thromboangeitis obliterans
Limb
Lower limb
Cardiovascular disease
Arterial disease of the limb
Arterial occlusive disease
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Summary:In an effort to determine the current incidence and clinical course of Buerger's disease, we reviewed the records of over 700 patients with small artery disease who were evaluated at Oregon Health Sciences University during a 15 year period. We identified 26 patients who met rigid criteria for the diagnosis of Buerger's disease. An analysis of the management and extended follow-up of these patients has indicated that Buerger's disease, although rare, is a real clinical entity which can be diagnosed objectively. The relatively high rate of limb loss (31 percent of patients) documents the virulence of Buerger's disease involving the lower extremities. No major upper extremity amputations were required, and no patient lost further tissue after cessation of smoking. These findings and the low mortality rate in this study stand in contrast to many previous reports and may aid in establishing the current natural history of Buerger's disease in North America.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0002-9610
1879-1883
DOI:10.1016/0002-9610(87)90301-1