Artificial metallonucleases
The development of synthetic agents able to hydrolytically cleave DNA with high efficiency and selectivity is a fascinating challenge that will show the way to obtaining artificial nucleases able to compete with the natural enzymes. This Feature Article highlights the progress reported toward the re...
Saved in:
Published in | Chemical communications (Cambridge, England) no. 20; p. 2540 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
28.05.2005
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Summary: | The development of synthetic agents able to hydrolytically cleave DNA with high efficiency and selectivity is a fascinating challenge that will show the way to obtaining artificial nucleases able to compete with the natural enzymes. This Feature Article highlights the progress reported toward the realization of synthetic nucleases with particular attention to the strategies that can be pursued to improve efficiency and sequence selectivity. |
---|---|
ISSN: | 1359-7345 |
DOI: | 10.1039/b418164f |