DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications
We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microo...
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Published in | Lab on a chip Vol. 12; no. 24; pp. 5218 - 5224 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
21.12.2012
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Subjects | |
Online Access | Get full text |
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Summary: | We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 1473-0197 1473-0189 |
DOI: | 10.1039/c2lc40921f |