In vitro adrenal cortex lesions characterization by NMR spectroscopy

• Published in: Magnetic resonance imaging Vol. 5; no. 5; pp. 339 - 344
• Main Authors: Leroy-Willig, A., Roucayrol, J.C., Luton, J.P., Courtieu, J., Niesenbaum, N., Louvel, A.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 1987; Elsevier Science
• Subjects: Adenoma - analysis; Adolescent; Adrenal; Adrenal Cortex Diseases - diagnosis; Adrenal Cortex Diseases - metabolism; Adrenal Cortex Neoplasms - analysis; Adult; Aged; Biological and medical sciences; Body Water - analysis; Child; Diagnosis, Differential; Endocrine glands; Female; Humans; Hyperplasia - metabolism; Investigative techniques, diagnostic techniques (general aspects); Lipids; Lipids - analysis; Magnetic Resonance Spectroscopy; Male; Medical sciences; Middle Aged; NMR; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Tumor; Lipids; Tumor; NMR; Adrenal; Endocrinopathy; Human; Adrenal cortex diseases; Adrenal cortex; Medical imagery; Nuclear magnetic resonance imaging; In vitro
• ISSN: 0730-725X; 1873-5894
• DOI: 10.1016/0730-725X(87)90123-8

Percentage of lipid content of 22 adrenal cortex lesions and their water proton longitudinal relaxation time were measured in vitro at 60 MHz. Although water relaxation times obtained on benign and malignant samples overlap each other, measurements of the percentage of lipids performed on the same tissues allow us to distinguish the two pathologies. This specific tool of characterization should be possible to obtain through in vivo spectroscopic imaging techniques.