Application and prospect of exosomes combined with Chinese herbal medicine in orthopedics

Exosomes are vesicle-like bodies of that are actively secreted by cells to the extracellular surrounding with a diameter of 40–100 nm. They have several physiological functions, such as cell-cell communication, antitumor immunity, and angiogenesis promotion. Exosomes have many important roles and ar...

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Published inJournal of herbal medicine Vol. 35; p. 100589
Main Authors Liang, Qianxin, Jiang, Chaoxin, Zhao, Qing, Guo, Zhaodi, Xie, Manlin, Zou, Yanfang, Cai, Xiuping, Su, Jing, He, Zhiliang, Zhao, Kewei
Format Journal Article
LanguageEnglish
Published Elsevier GmbH 01.09.2022
Subjects
Chinese herbal medicines
Exosome
Orthopedics
Exosome
Orthopedics
Chinese herbal medicines
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Summary:Exosomes are vesicle-like bodies of that are actively secreted by cells to the extracellular surrounding with a diameter of 40–100 nm. They have several physiological functions, such as cell-cell communication, antitumor immunity, and angiogenesis promotion. Exosomes have many important roles and are extensively distributed in various fluids throughout the body, and therefore, they are of significant interest to researchers in diverse fields. Based on the characteristics and physiological functions of exosomes, this review summarizes the research progression regarding the role of exosomes in the field of orthopedics in recent years and highlights the association between exosomes and Chinese herbal medicines, to contribute to the application of exosomes in orthopedics and Chinese herbal medicines in the future. Moreover,the combined application of Chinese herbal medicines and exosomes can promote the modernization of Chinese herbal medicines.
ISSN:2210-8033
DOI:10.1016/j.hermed.2022.100589