A Prospective Study on 132 Cases of Ocular Palsy

Objectives: In this prospective study, we used one diagnostic protocol to establish an early diagnosis in patients with ocular palsies in absence of other neurological findings. Materials and Methods: The study was performed on a consecutive series of 132 patients who visited our Neurological Depart...

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Bibliographic Details
Published inEuropean neurology Vol. 70; no. 1-2; pp. 10 - 15
Main Authors Castelluccia, A., Nociti, V., Frisullo, G., Batocchi, A.P.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 01.08.2013
Subjects
Adult
Blepharoptosis - diagnosis
Blepharoptosis - etiology
Diplopia - diagnosis
Diplopia - etiology
Female
Humans
Male
Middle Aged
Oculomotor Nerve Diseases - diagnosis
Oculomotor Nerve Diseases - etiology
Original Paper
Prospective Studies
Ocular palsies
Ptosis
Internuclear ophthalmoplegia
Diplopia
Ocular myasthenia
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Summary:Objectives: In this prospective study, we used one diagnostic protocol to establish an early diagnosis in patients with ocular palsies in absence of other neurological findings. Materials and Methods: The study was performed on a consecutive series of 132 patients who visited our Neurological Department for ptosis and/or diplopia in absence of other neurological signs, using the same diagnostic protocol. Results: An etiological diagnosis was made in 74% of cases during a mean time of 17 ± 23 months from symptom onset. Myasthenia gravis was the most common diagnosis (n = 60, 45.5%). Thirty-four cases (26%) remained undiagnosed in spite of a follow-up lasting 32 ± 33 months on average. Conclusions: Identifying the cause of an isolated ocular palsy can be difficult, and an extended follow-up time does not aid in further establishment of the diagnosis.
ISSN:0014-3022
1421-9913
DOI:10.1159/000348717