An unusual case of three synchronous tumors in a young woman

• Published in: Tumori Vol. 91; no. 3; p. 267
• Main Authors: Longo, Raffaele, Carillio, Guido, Torrisi, Antonietta, Tocco, Maria Pia, Grassi, Giovanni Battista, Marrese, Renato, Fanasca, Angelo, Balistreri, Paolo, Gasparini, Giampietro
• Format: Journal Article
• Language: English
• Published: United States 01.05.2005
• Subjects: Female; Humans; Liposarcoma - diagnosis; Liposarcoma - pathology; Liposarcoma - surgery; Lung Neoplasms - diagnosis; Middle Aged; Neoplasms, Multiple Primary - diagnosis; Neoplasms, Multiple Primary - pathology; Neoplasms, Multiple Primary - surgery; Positron-Emission Tomography; Pulmonary Sclerosing Hemangioma - diagnosis; Pulmonary Sclerosing Hemangioma - pathology; Pulmonary Sclerosing Hemangioma - surgery; Treatment Outcome; Ureteral Neoplasms - diagnosis; Ureteral Neoplasms - pathology; Ureteral Neoplasms - surgery
• ISSN: 0300-8916
• DOI: 10.1177/030089160509100312

The occurrence in the same young patient of three synchronous tumors deriving from different embryogenic tissues and without a clear correlation with a common etiopathogenic factor is very unusual. We report a case of a Caucasian woman submitted to wide resection of a large retroperitoneal liposarcoma and right radical nephrectomy for suspected tumor infiltration. Histological examination of the right ureter and renal pelvis showed the presence of a multifocal urothelial carcinoma that was clinically asymptomatic. Two months later, during follow-up, chest X-ray and computed tomography documented a coin lesion of the upper left lung, confirmed by positron emission tomography. This nodule was surgically removed and examined histologically, resulting in a diagnosis of sclerosing hemangioma. The patient is alive without evidence of recurrent disease.