Treatment of hypertension for patients with diastolic dysfunction

Diastolic dysfunction is a poorly understood pathophysiological entity; its importance is magnified by the increasing prevalence of diastolic heart failure. Forty-six million people in the US are experiencing heart failure and 550000 new cases are diagnosed annually. A large percentage of these pati...

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Bibliographic Details
Published inCurrent opinion in cardiology Vol. 18; no. 4; p. 272
Main Authors Krishnan, Prakash, Ventura, Hector O, Uber, Patricia A, Arcement, Lee M, Mehra, Mandeep R
Format Journal Article
LanguageEnglish
Published United States 01.07.2003
Subjects
Adrenergic beta-Antagonists - therapeutic use
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Calcium Channel Blockers - therapeutic use
Comorbidity
Diastole
Heart Failure - epidemiology
Heart Failure - physiopathology
Humans
Hypertension - drug therapy
Hypertension - epidemiology
Hypertension - physiopathology
Hypertrophy, Left Ventricular - drug therapy
Mineralocorticoid Receptor Antagonists - therapeutic use
Ventricular Dysfunction, Left - epidemiology
Ventricular Dysfunction, Left - physiopathology
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Summary:Diastolic dysfunction is a poorly understood pathophysiological entity; its importance is magnified by the increasing prevalence of diastolic heart failure. Forty-six million people in the US are experiencing heart failure and 550000 new cases are diagnosed annually. A large percentage of these patients with heart failure have a normal or nearly normal left-ventricular ejection fraction. Isolated diastolic dysfunction may be associated with an increased mortality. One of the major causes of diastolic dysfunction is hypertension. Advances in diagnosis and treatment strategies may improve the clinical outcome for patients with diastolic dysfunction.
ISSN:0268-4705
DOI:10.1097/00001573-200307000-00006