ESR and electrochemical study of 1,2-disubstituted 5-nitroindazolin-3-ones and 2-substituted 3-alkoxy-5-nitro-2H-indazoles: reactivity and free radical production capacity in the presence of biological systems
Two families of 5-nitroindazole derivatives were electrochemically studied in an aprotic solvent using cyclic voltammetry (CV) technique. The produced nitro-anion radical species were characterized using electron spin resonance spectroscopy (ESR). Also, we examined the interaction between the radica...
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Published in | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 75; no. 1; pp. 375 - 380 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
01.01.2010
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Subjects | |
Online Access | Get full text |
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Summary: | Two families of 5-nitroindazole derivatives were electrochemically studied in an aprotic solvent using cyclic voltammetry (CV) technique. The produced nitro-anion radical species were characterized using electron spin resonance spectroscopy (ESR). Also, we examined the interaction between the radical species generated from nitroindazole derivatives and glutathione (GSH). Moreover, the capacity of intraparasite and intramammals-free radical production, through ESR spectroscopy, was performed. |
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ISSN: | 1386-1425 1873-3557 |
DOI: | 10.1016/j.saa.2009.10.044 |