Erythema Scarlatiniforme Desquamativum Recidivans: A Rare and Puzzling Condition

Recurrent erythema scarlatiniforme desquamativum recidivans (ESDR), also known as Féréol-Besnier disease, is a rare condition marked by a recurrent erythematous rash that is followed by extensive desquamation, primarily affecting the palms and soles. It is often preceded by prodromal symptoms such a...

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Published inCurēus (Palo Alto, CA) Vol. 16; no. 9; p. e68981
Main Authors Benbrahim Ansari, Ghita, Naji, Houda, Aboufaris, Hanan, Bouayed, Kenza
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 09.09.2024
Cureus
Subjects
Bacterial infections
Dermatology
Erythema
Females
Fever
Headaches
Infections
Laboratories
Leukocytes
Neutrophils
Pain
Pediatrics
Rheumatology
Skin care products
Viral infections
children
recurrent scarlatiniforme rash
prodromal phase
desquamation
uncommon condition
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Summary:Recurrent erythema scarlatiniforme desquamativum recidivans (ESDR), also known as Féréol-Besnier disease, is a rare condition marked by a recurrent erythematous rash that is followed by extensive desquamation, primarily affecting the palms and soles. It is often preceded by prodromal symptoms such as malaise, headache, myalgias, digestive issues, and fever. The exact pathogenesis remains unknown, and diagnosis can be challenging due to its resemblance to various infectious, auto-inflammatory, or allergic conditions, leading to diagnostic variability. Given that most reported cases are over 50 years old, our objective is to highlight this rare and enigmatic pathology through a typical case of the generalized variant of ESDR in a 13-year-old girl. We aim to increase physician awareness of this condition and provide reassurance to both parents and their child regarding its benign nature.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.68981