Extraction, isolation and bioactivity of oligostilbenes from oil peony seed shells
An efficient strategy for the extraction of total oligostilbenes extract (TOE) from oil peony seed shells was developed. The chemical constituents, the antimicrobial and antitumor activities of TOE were also measured. Based on the results, the optimum conditions were as follows: an ultrasonic extrac...
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Published in | Food bioscience Vol. 41; p. 101004 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
01.06.2021
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Subjects | |
Online Access | Get full text |
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Summary: | An efficient strategy for the extraction of total oligostilbenes extract (TOE) from oil peony seed shells was developed. The chemical constituents, the antimicrobial and antitumor activities of TOE were also measured. Based on the results, the optimum conditions were as follows: an ultrasonic extraction temperature of 64.0 °C, an ultrasonic extraction time of 25.0 min, a liquid-to-solid ratio of 25.0 mL/g, and an ethanol concentration of 66.0%. With these conditions, the extraction yield of TOE was 20.5%. Bioactivity assays showed that the TOE had varying degrees of antibacterial activity and strong antitumor activity in vitro. Twelve oligostilbenes were isolated from the TOE, and trans-gnetin H and suffruficosol B were the main compounds in the oil peony seed shells. These results suggested that the TOE from oil peony seed shells can be prepared as value-added products for their good antimicrobial and antitumor activities.
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•RSM was used to optimize the UAE conditions for the extraction of TOE from oil peony seed shells.•The antimicrobial and antitumor activities of TOE were assessed.•Twelve oligostilbenes were isolated from the TOE of oil peony seed shells.•Oligostilbene compounds were the main active substances in oil peony seed shells.•The TOE might be developed into a food additives because of its good biological activities. |
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ISSN: | 2212-4292 2212-4306 |
DOI: | 10.1016/j.fbio.2021.101004 |