Teriflunomide-Induced Palmoplantar Pustular Psoriasis: Case Report and Review of the Literature

Teriflunomide is a once-daily oral immunomodulatory disease-modifying treatment for multiple sclerosis (MS). Skin reactions are an infrequent side effect of teriflunomide. Here, we present the case of a 52-year-old female patient with ankylosing spondylitis who was consulted for demyelinating lesion...

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Published inCurēus (Palo Alto, CA) Vol. 15; no. 8; p. e42845
Main Authors Demirel Ozbek, Ezgi, Akdogan, Neslihan, Ates Ozdemir, Deniz, Acar Ozen, Nazire Pinar, Tuncer, Aslı
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 02.08.2023
Cureus
Subjects
Arthritis
Case reports
Dermatology
Enzymes
Multiple sclerosis
Nervous system
Neurology
Neutrophils
Patients
Psoriasis
Skin
Steroids
Tumor necrosis factor-TNF
Young adults
Ankara Turkey
United States > US
Turkey
teriflunamide
adverse effects
multiple sclerosis
immunomodulatory treatments
palmoplantar pustular psoriasis
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Summary:Teriflunomide is a once-daily oral immunomodulatory disease-modifying treatment for multiple sclerosis (MS). Skin reactions are an infrequent side effect of teriflunomide. Here, we present the case of a 52-year-old female patient with ankylosing spondylitis who was consulted for demyelinating lesions and limb weakness. She was diagnosed with multiple sclerosis and started treatment with teriflunomide. Palmoplantar pustular psoriasis developed after three weeks of treatment initiation. It is a rare side effect related to teriflunomide.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Report-1
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.42845