Synthesis of secondary amides by direct amidation using polymer supported copper(II) complex

• Published in: Polyhedron Vol. 148; pp. 195 - 202
• Main Authors: Renuka, M.K., Gayathri, V.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.07.2018; Elsevier
• Subjects: Benzaldehyde; Benzyl amine; Chemistry; Chemistry, Inorganic & Nuclear; Crystallography; Cu(PS-BBMA)Cl2; Direct amidation; Heterogeneous catalysis; Physical Sciences; Science & Technology; Benzyl amine; Heterogeneous catalysis; Direct amidation; Cu(PS-BBMA)Cl2; Benzaldehyde; TRANSFORMATION; CARBENE; OXIDATIVE AMIDATION; COUPLING REAGENTS; BOND FORMATION; ALDEHYDES; CATALYST; PEPTIDE; AMINE HYDROCHLORIDE SALTS; ALCOHOLS; Cu(PS-BBMA)Cl-2
• ISSN: 0277-5387
• DOI: 10.1016/j.poly.2018.04.004

The polymer-supported bis(benzimidazolylmethyl)amine copper complex Cu(PS-BBMA)Cl2 was synthesized and characterized successfully and investigated its catalytic activity towards direct amidation reaction. [Display omitted] A new polymer supported Cu(II) complex has been synthesized and characterized by CHN analyses, IR and UV–Vis spectral studies, ESR and thermogravimetric analyses, ICP-OES, surface area measurements. This complex was screened for their catalytic study towards the direct amidation reaction. The effects of solvents, reaction time, temperature and catalyst amount for the direct formation of amides from aldehydes and benzylamine with the aid of heterogeneous copper complex were reported. The polymer supported Cu(II) catalyst could be reused more than five times without appreciable loss of its initial activity. The plausible reaction mechanism has been proposed. The catalytic activity of the unsupported complex was also compared with the polymer supported Cu(II) complex.