Revisiting natural deep eutectic solvents (NADES) as extraction media and ready-to-use purposes

The assessment of efficient and sustainable methods for extracting high-value compounds from natural products aligns with some of the statements proposed by the 12 Principles of Green Chemistry and 17 Sustainable Development Goals. Replacing hazardous chemicals with safer alternatives, such as Natur...

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Published inTrAC, Trends in analytical chemistry (Regular ed.) Vol. 175; p. 117726
Main Authors Bragagnolo, Felipe Sanchez, Strieder, Monique Martins, Pizani, Rodrigo Stein, de Souza Mesquita, Leonardo M., González-Miquel, María, Rostagno, Maurício Ariel
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.06.2024
Subjects
Alternative solvents
Biorefinery
Circular economy
NADES
Natural products
Sustainable extraction
Biorefinery
Circular economy
Natural products
NADES
Alternative solvents
Sustainable extraction
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Summary:The assessment of efficient and sustainable methods for extracting high-value compounds from natural products aligns with some of the statements proposed by the 12 Principles of Green Chemistry and 17 Sustainable Development Goals. Replacing hazardous chemicals with safer alternatives, such as Natural Deep Eutectic Solvents (NADES), offers a promising and environmentally friendly approach. This review provides a comprehensive analysis of the composition of NADES, associated extraction techniques, and advancements in their use as an extraction media for bioactive compounds from their first report in 2013 until 2023. Moreover, an in-depth discussion of the terminology of NADES is presented and an updated and new term is suggested for specific combinations: Mixtures based on Natural Compounds (MINACs). Finally, prospective applications of such solvents are provided, complemented by insights into emerging trends and their potential to produce ready-to-use extracts. [Display omitted] •NADES have emerged as green alternatives to conventional solvents.•Modern techniques, especially UAE, are employed with NADES.•A new term is proposed: Mixtures based on Natural Compounds (MINACs).•Ready-to-use extracts show high potential for the cosmetic and food industries.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2024.117726