Lymphomatoid Papulosis With DUSP22 Rearrangement in a Patient With a Historical Diagnosis of Primary Cutaneous Anaplastic Large Cell Lymphoma
Lymphomatoid papulosis (LyP) with rearrangement is an uncommon subtype of lymphomatoid papulosis featured histologically by two distinct patterns of epidermotropic cells, weakly CD30+ small- to medium-sized T-cells and a dermal infiltrate of strongly CD30+ medium- to large-sized T-cells. rearran...
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Published in | Curēus (Palo Alto, CA) Vol. 16; no. 8; p. e66022 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Cureus Inc
02.08.2024
Cureus |
Subjects | |
Online Access | Get full text |
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Summary: | Lymphomatoid papulosis (LyP) with
rearrangement is an uncommon subtype of lymphomatoid papulosis featured histologically by two distinct patterns of epidermotropic cells, weakly CD30+ small- to medium-sized T-cells and a dermal infiltrate of strongly CD30+ medium- to large-sized T-cells.
rearrangement is detected more frequently in anaplastic large cell lymphoma (ALCL) than in LyP. Primary cutaneous anaplastic large cell lymphoma (pcALCL) cases can also show a similar biphasic CD30 staining pattern. LyP with
rearrangement has a more indolent clinical course than pcALCL and is more likely to regress without treatment. Herein, we report a unique case of LyP with
rearrangement diagnosed in an 81-year-old female with a historical diagnosis of pcALCL, made 20 years prior. |
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Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
ISSN: | 2168-8184 2168-8184 |
DOI: | 10.7759/cureus.66022 |