Papillary Thyroid Cancer in a Patient With Graves' Disease and Hyperfunctioning (Hot) Thyroid Nodules: An Unexpected Presentation

Hyperfunctioning (hot) nodules are considered benign while cold nodules are associated with a higher risk of thyroid cancer. In this case report, we present a patient diagnosed with Graves' disease and later found to have papillary thyroid carcinoma (Bethesda VI), confirmed by fine needle aspir...

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Published inCurēus (Palo Alto, CA) Vol. 16; no. 7; p. e64373
Main Authors Jamal, Fares, Hakobyan, Narek, Siddiqui, Samrah
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 11.07.2024
Cureus
Subjects
Antibodies
Biopsy
Cardiovascular disease
Cellular biology
Chronic obstructive pulmonary disease
Endocrinology/Diabetes/Metabolism
Graves disease
Hormones
Immunoglobulins
Internal Medicine
Iodine
Lymphatic system
Metastasis
Oncology
Patients
Scintigraphy
Thyroid cancer
Thyroidectomy
Tumors
Ultrasonic imaging
thyroid-stimulating hormone
thyroid nodule
hot nodules
papillary carcinoma of thyroid
ultrasonography
thyroid cancer
graves' disease
thyroid-stimulating immunoglobulin (tsi)
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Summary:Hyperfunctioning (hot) nodules are considered benign while cold nodules are associated with a higher risk of thyroid cancer. In this case report, we present a patient diagnosed with Graves' disease and later found to have papillary thyroid carcinoma (Bethesda VI), confirmed by fine needle aspiration (FNA) biopsy, with regional metastasis to the neck and possible metastasis to the lungs. This paper demonstrates that hot nodules are not always benign, and could be associated with malignancy.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.64373