Polymer/inorganic nanohybrids: An attractive materials for analysis and sensing

• Published in: TrAC, Trends in analytical chemistry (Regular ed.) Vol. 140; p. 116273
• Main Authors: Sun, Jiefang, Ma, Qian, Xue, Dingshuai, Shan, Wenchong, Liu, Runqing, Dong, Baolei, Zhang, Jing, Wang, Zhanhui, Shao, Bing
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.07.2021
• Subjects: Analysis; Polymer/inorganic nanohybrids; Properties; Recent progress; Sensing; Structures; Polymer/inorganic nanohybrids; Sensing; Structures; Recent progress; Properties; Analysis
• ISSN: 0165-9936; 1879-3142
• DOI: 10.1016/j.trac.2021.116273

Fabrication of robust, sensitive and selective biosensors holds much promise, but still facing challenges. Currently, functional polymers have demonstrated their outstanding properties for constructing high performed analysis by integrating with various inorganic nanomaterials. In this review, we start from briefly introducing the typical characters of functional polymers as ligands, and then the commonly used synthesis strategies are summarized to offer valuable guides for constructing polymer/inorganic nanohybrids. Subsequently, we provided some representative polymer/inorganic nano-biosensors with outstanding capacities for in analytical applications and further emphasize the influence of the structures and properties of polymer grafted nanohybrids. Finally, a perspective on the future developments of polymer/inorganic nanohybrid based assays would be proposed, which outline possible direction to be pursued for causing disruptive improvements. We hope this review could help researchers become acclimated with the current status of this field, and inspire more design and construction of assays to satisfy ever increasing real demands. •Functional polymers offer attractive alternatives to engineer nano-sensing interfaces.•Common kinds and integration strategies of polymer on inorganic nanoparticles have been briefly classified and presented.•Current innovations of polymer/inorganic nanohybrids in analytical and sensing are comprehensively introduced.•Research prospects and directions of polymer/inorganic nanohybrids in analytical field are identified.