Surface-enhanced Raman scattering inspired by programmable nucleic acid isothermal amplification technology

• Published in: TrAC, Trends in analytical chemistry (Regular ed.) Vol. 143; p. 116401
• Main Authors: Yuan, Changjing, Fang, Jie, de la Chapelle, Marc Lamy, Zhang, Yang, Zeng, Xiaojun, Huang, Guorong, Yang, Xiang, Fu, Weiling
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2021
• Subjects: Catalytic hairpin assembly (CHA); Entropy-driven catalytic reaction (EDR); Exponential amplification reaction (EXPAR); Hybridization chain reaction (HCR); Loop-mediated isothermal amplification (LAMP); Nucleic acid isothermal amplification (NAIA); Recombinase polymerase amplification (RPA); Rolling circle amplification (RCA); Strand displacement amplification (SDA); Surface-enhanced Raman scattering (SERS); Recombinase polymerase amplification (RPA); Exponential amplification reaction (EXPAR); Loop-mediated isothermal amplification (LAMP); Hybridization chain reaction (HCR); Catalytic hairpin assembly (CHA); Strand displacement amplification (SDA); Surface-enhanced Raman scattering (SERS); Nucleic acid isothermal amplification (NAIA); Entropy-driven catalytic reaction (EDR); Rolling circle amplification (RCA)
• ISSN: 0165-9936; 1879-3142
• DOI: 10.1016/j.trac.2021.116401

Surface-enhanced Raman scattering (SERS) is a mature vibrational spectroscopic technique, and its application in chemical, material, especially life sciences is increasing rapidly. SERS alone cannot meet the demands of current analysis, while the desirable features of nucleic acid isothermal amplification (NAIA) make the simple, economical and flexible SERS become a reality. SERS has been combined with NAIA to provide researchers with more sensitive and precise analysis specifications in biological samples. However, there is no comprehensive review of the SERS analysis combined with NAIA yet. The present review introduces the development of SERS briefly and summarizes the necessary theory for understanding SERS and NAIA. The SERS analyses integrated with NAIA are the centerpiece of this review. They cover a broad range of topics, for example, hybridization chain reaction (HCR), catalytic hairpin assembly (CHA), entropy-driven catalytic reaction (EDR), strand displacement amplification (SDA), recombinase polymerase amplification (RPA), exponential amplification reaction (EXPAR), rolling circle amplification (RCA), and loop-mediated isothermal amplification (LAMP). In the end, the challenges and prospective opinions of the SERS in application are discussed. •The applications of nucleic acid isothermal amplification in SERS are systematically reviewed for the first time.•The key concepts of SERS and nucleic acid isothermal amplification are introduced.•The recent progress in the applications of nucleic acid isothermal amplification in SERS assay is summarized in detail.•The challenges and prospects of SERS application are discussed.