Neural regulation of compensatory enlargement of the parotid gland of the rat

The role of the innervation in mediating compensatory enlargement of the parotid gland of the rat after partial desalivation was examined. The results of denervation experiments show that full compensatory growth requires both parasympathetic and sympathetic innervation. The presence of the parasymp...

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Bibliographic Details
Published inCell and tissue research Vol. 187; no. 1; p. 147
Main Authors Hall, H.D, Schneyer, C.A. (Vanderbild Univ., Nashville, Tennessee (USA). School of Medicine)
Format Journal Article
LanguageEnglish
Published Germany 14.02.1978
Subjects
Animals
Cell Count
Denervation
Male
Organ Size
Parasympathetic Nervous System
Parotid Gland - innervation
Parotid Gland - pathology
Parotid Gland - physiology
Rats
Sympathetic Nervous System
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Summary:The role of the innervation in mediating compensatory enlargement of the parotid gland of the rat after partial desalivation was examined. The results of denervation experiments show that full compensatory growth requires both parasympathetic and sympathetic innervation. The presence of the parasympathetic innervation alone results in an increase in the number of cells, but not the size of the cells. The sympathetic innervation alone does not mediate either response. We, therefore, conclude that the two types of innervation have a synergistic action on the parotid to produce the maximal compensatory response, which includes an increase in both number and size of acinar cells.
Bibliography:L70
784B410
L50
ISSN:0302-766X
1432-0878
DOI:10.1007/BF00220626