Post-esophagectomy Anastomosis Leak: A 10-Year Experience at a Specialized Center for Cancer Surgeries in Pakistan

Esophageal cancer has been reported to be the seventh most common cancer and the sixth most common cause of mortality. Use of advanced diagnostic techniques has increased the detection of preoperative metastases and resulted in better patient selection for further management by curative surgery. We...

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Published inCurēus (Palo Alto, CA) Vol. 15; no. 2; p. e34777
Main Authors Shafiq, Ahsan, Azad, Junaid, Batool, Shan-E-Zahra, Butt, Usman Ismat, Umar, Muhammad, Syed, Aamir, Khattak, Shahid
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 08.02.2023
Cureus
Subjects
Cancer surgery
Cancer therapies
Endoscopy
Esophageal cancer
Gastroesophageal reflux
Gender
General Surgery
Morbidity
Mortality
Oncology
Patients
Risk factors
Surgical anastomosis
Tumors
Variables
the: transhiatal esophagectomy
transthoracic esophagectomy
specialized-services
ec- esophageal cancer
oesophageal cancer
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Summary:Esophageal cancer has been reported to be the seventh most common cancer and the sixth most common cause of mortality. Use of advanced diagnostic techniques has increased the detection of preoperative metastases and resulted in better patient selection for further management by curative surgery. We carried out a study to evaluate the outcome of esophagectomy at our institute in terms of acute leak, mortality and hospital stay. We also looked at various preoperative, intraoperative and postoperative risk factors contributing to leak after esophagectomy. We evaluated 589 patients during the period from January 2009 to December 2019. All these patients underwent elective esophagectomy for esophageal cancer at our hospital. Out of these, leak was seen in 30 patients (5.1%). We found no statistically significant difference when evaluating patient and tumour characteristics of patients who developed leak against those who did not. We also didn't find any significant difference in intraoperative or postoperative factors between the two groups. Proper preoperative evaluation and optimization are necessary to overcome various patient co-morbidities. On the basis of our study we conclude that when performed in high-volume centers with an adequately trained multi-disciplinary team approach, esophagectomy for carcinoma has a good outcome.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.34777