The liver-spleen scan in systemic amyloidosis: a clue to the diagnosis

The clinical findings in cirrhosis and systemic amyloidosis may be similar, leading to difficulties in diagnosis. We studied three patients with systemic amyloidosis with a 99mTc sulfur colloid liver-spleen scan. In all three patients, uptake by the spleen was less than the liver, in contrast with t...

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Bibliographic Details
Published inJournal of clinical gastroenterology Vol. 16; no. 4; p. 340
Main Authors Straub, R F, Boyer, T D
Format Journal Article
LanguageEnglish
Published United States 01.06.1993
Subjects
Aged
Amyloidosis - diagnostic imaging
Female
Humans
Liver Diseases - diagnostic imaging
Male
Middle Aged
Radionuclide Imaging
Splenic Diseases - diagnostic imaging
Technetium Tc 99m Sulfur Colloid
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Summary:The clinical findings in cirrhosis and systemic amyloidosis may be similar, leading to difficulties in diagnosis. We studied three patients with systemic amyloidosis with a 99mTc sulfur colloid liver-spleen scan. In all three patients, uptake by the spleen was less than the liver, in contrast with the increased splenic uptake seen in patients with cirrhosis. The liver-spleen scan may be a useful tool in differentiating patients with cirrhosis from those with systemic amyloidosis when clinical findings fail to give the proper diagnosis.
ISSN:0192-0790
DOI:10.1097/00004836-199306000-00017