The Use of Acellular Tissue Matrices in Gender-Affirming Surgery: Review of the Literature and Institutional Experience

Wound healing complications are not uncommon after genital gender-affirming surgery and can pose significant challenges for the reconstructive surgeon. Acellular tissue matrices are products that contain extracellular matrix compounds without living cells and are used to expedite and improve wound h...

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Bibliographic Details
Published inAdvanced biology Vol. 8; no. 9; p. e2300507
Main Authors Alba, Brandon, Weinstein, Brielle, Arnold, Sydney H, Jacobs, Kristin M, Schechter, Loren
Format Journal Article
LanguageEnglish
Published Germany 01.09.2024
Subjects
Acellular Dermis
Female
Humans
Male
Sex Reassignment Surgery - methods
Wound Healing
gender diverse
vaginoplasty
phalloplasty
gender‐affirming surgery
transgender
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Summary:Wound healing complications are not uncommon after genital gender-affirming surgery and can pose significant challenges for the reconstructive surgeon. Acellular tissue matrices are products that contain extracellular matrix compounds without living cells and are used to expedite and improve wound healing. Some of these products have been described for a variety of different indications in gender-affirming surgery.  In this paper, the authors present a review of the current literature on the use of acellular tissue matrices in gender-affirming surgery as well as the authors' institutional experience in using these products.
ISSN:2701-0198
DOI:10.1002/adbi.202300507