Proteinuria and progression of renal disease: therapeutic implications

The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal functi...

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Bibliographic Details
Published inCurrent opinion in nephrology and hypertension Vol. 6; no. 2; p. 133
Main Authors Gansevoort, R T, Navis, G J, Wapstra, F H, de Jong, P E, de Zeeuw, D
Format Journal Article
LanguageEnglish
Published England 01.03.1997
Subjects
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Animals
Diabetic Nephropathies - physiopathology
Diabetic Nephropathies - prevention & control
Disease Progression
Diuretics - therapeutic use
Glomerular Filtration Rate
Humans
Kidney - physiopathology
Kidney Diseases - physiopathology
Kidney Diseases - prevention & control
Predictive Value of Tests
Proteinuria - diet therapy
Proteinuria - drug therapy
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Summary:The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.
ISSN:1062-4821
DOI:10.1097/00041552-199703000-00005