A Contemporaneous Onset of Eosinophilic Granulomatosis with Polyangiitis and Myasthenia Gravis: A Case Report

Autoimmune neuromuscular disorders in patients with eosinophilic granulomatosis with polyangiitis (EGPA) are relatively uncommon. Although two cases of myasthenia gravis (MG) comorbid with EGPA have been reported, both patients developed EGPA several years after starting immunosuppressive treatment...

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Published inInternal Medicine p. 2872-23
Main Authors Sato, Daisuke, Nishiguchi, Sho, Yamamoto, Daisuke, Ishioka, Kunihiro, Kakutani, Takuya, Watai, Kentaro, Taniguchi, Masami
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 2024
Subjects
autoimmune neuromuscular disorders
Eosinophilic granulomatosis with polyangiitis
myasthenia gravis
myasthenia gravis
autoimmune neuromuscular disorders
Eosinophilic granulomatosis with polyangiitis
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Summary:Autoimmune neuromuscular disorders in patients with eosinophilic granulomatosis with polyangiitis (EGPA) are relatively uncommon. Although two cases of myasthenia gravis (MG) comorbid with EGPA have been reported, both patients developed EGPA several years after starting immunosuppressive treatment for MG. We herein report a 75-year-old man with a rare co-occurrence of EGPA and MG that developed simultaneously and was successfully treated with immunosuppressive therapy. Distinguishing the neurological symptoms of EGPA from complications of other neurological autoimmune diseases, such as MG, is crucial, especially in patients with eosinophilia.
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content type line 23
ISSN:0918-2918
1349-7235
1349-7235
DOI:10.2169/internalmedicine.2872-23