A case of autoimmune encephalitis in a patient with a solitary intracranial plasmacytoma

A 65-year-old woman presented with fever and abnormal behavior. Magnetic resonance imaging showed swelling of the left medial temporal lobe and an intracranial extra-axial occipital tumor. While her neurological symptoms improved after the administration of corticosteroid therapy under the suspicion...

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Published inInternal Medicine p. 2888-23
Main Authors Mizutani, Keisuke, Sakurai, Keita, Uchida, Yuto, Hashimoto, Ken, Kajiguchi, Tomohiro, Takahashi, Yukitoshi, Yuasa, Hiroyuki, Takada, Koji, Matsukawa, Noriyuki
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 2024
Subjects
anti-glutamate receptor
autoimmune encephalitis
paraneoplastic syndromes
solitary plasmacytoma
autoimmune encephalitis
paraneoplastic syndromes
solitary plasmacytoma
anti-glutamate receptor
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Summary:A 65-year-old woman presented with fever and abnormal behavior. Magnetic resonance imaging showed swelling of the left medial temporal lobe and an intracranial extra-axial occipital tumor. While her neurological symptoms improved after the administration of corticosteroid therapy under the suspicion of autoimmune encephalitis, the occipital tumor unexpectedly shrank, and the diagnosis of a solitary plasmacytoma was confirmed by biopsy. Additional examinations revealed elevated anti-glutamate receptor antibodies in the cerebrospinal fluid. The patient was diagnosed with autoimmune encephalitis concurrent with an intracranial solitary plasmacytoma. Central nervous system involvement can be considered a neurological complication in patients with a solitary plasmacytoma.
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content type line 23
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.2888-23