Choroid plexus adenoma: case report and review of the literature

• Published in: Child's nervous system Vol. 21; no. 5; pp. 410 - 415
• Main Authors: Aquilina, Kristian, Nanra, Jagdeep S, Allcutt, David A, Farrell, Michael
• Format: Journal Article
• Language: English
• Published: Germany 01.05.2005
• Subjects: Adenoma - complications; Adenoma - metabolism; Adenoma - surgery; Choroid Plexus Neoplasms - complications; Choroid Plexus Neoplasms - metabolism; Choroid Plexus Neoplasms - surgery; Follow-Up Studies; Humans; Hydrocephalus - complications; Hydrocephalus - metabolism; Hydrocephalus - surgery; Immunohistochemistry - methods; Infant; Magnetic Resonance Imaging - methods; Male; Prealbumin - metabolism; S100 Proteins - metabolism; Ventriculoperitoneal Shunt - methods; Vimentin - metabolism
• ISSN: 0256-7040; 1433-0350
• DOI: 10.1007/s00381-004-1038-8

An 8-month-old infant with macrocephaly was found to have hydrocephalus and a cystic third ventricular tumour; biopsy of the tumour showed a choroid plexus adenoma. The tumour was attached to the ependymal lining and was strongly adherent to the walls and floor of the anterior third ventricle. After biopsy, it was felt that a radical resection would carry a high risk of injury to the floor of the third ventricle and cause new neurological deficits. Therefore, an external ventricular drain was inserted and bilateral ventriculo-peritoneal shunts were inserted 1 week post-operatively. In view of the benign nature of the tumour, no adjuvant radiotherapy or chemotherapy was given. There was no further tumour growth or clinical deterioration over a 6-year follow-up period.