The Antibacterial and Fungistatic Properties of Propamidine

1) The antibacterial spectrum of propamidine against representative grampositive and gram-negative organisms is presented. 2) The fungistatic action of propamidine has been studied as related to a number of the common superficial and deep pathogens. The sensitivity of some of these organisms compare...

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Bibliographic Details
Published inThe Journal of infectious diseases Vol. 76; no. 3; pp. 193 - 197
Main Author Elson, William O.
Format Journal Article
LanguageEnglish
Published The University of Chicago Press 01.05.1945
University of Chicago Press
Subjects
Adsorption
Antibacterials
Cations
Hydrogen
Ion concentration
Ions
Phosphates
Trichophyton
Wound infections
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Summary:1) The antibacterial spectrum of propamidine against representative grampositive and gram-negative organisms is presented. 2) The fungistatic action of propamidine has been studied as related to a number of the common superficial and deep pathogens. The sensitivity of some of these organisms compares with that of the gram-positive cocci. 3) The antagonistic effects of a phospholipid on the fungistatic action of propamidine is demonstrated. 4) The important relation of hydrogen ion concentration to bactericidal activity of propamidine has been studied and is discussed from the standpoint of competitive cationic adsorption.
Bibliography:ark:/67375/HXZ-ZV0JMZZC-W
istex:EEE02CD6FDA1F2BE2FD51702006BC586000E158C
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/76.3.193