Investigation on the properties of borate bonding agents: Ti6Al4V-porcelain bonding, chemical durability and preliminary cytotoxicity

• Published in: Materials Science & Engineering C Vol. 90; pp. 341 - 355
• Main Authors: Zhao, C.Q., Guo, S., Wu, S.Q., Luo, J.S., Lu, Y.J., Huang, T.T., Lin, J.X.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2018; Elsevier BV
• Subjects: Adhesion tests; Adhesive bonding; Aluminum oxide; Bend strength; Biocompatibility; Biomedical materials; Bonding agents; Bonding strength; Borate bonding agents; Borates - chemistry; Cell adhesion; Cell counters; Cell Survival - drug effects; Cells, Cultured; Chemical bonds; Chemical compounds; Chemical durability; Cholecystokinin; Cytotoxicity; Dental Porcelain - adverse effects; Dental Porcelain - chemistry; Durability; Emission analysis; Fourier transforms; Humans; Inductively coupled plasma; Infrared spectra; Infrared spectroscopy; Materials durability; Materials science; Metal Ceramic Alloys - adverse effects; Metal Ceramic Alloys - chemistry; Metal-porcelain bond strength; Microscopy, Electron, Scanning; NMR; Nuclear magnetic resonance; Optical emission spectroscopy; Organic chemistry; Osteosarcoma; Osteosarcoma cells; Porcelain; Properties (attributes); Spectrometry; Titanium - adverse effects; Titanium - chemistry; Titanium alloy; Titanium alloys; Titanium base alloys; Toxicity; X-Ray Diffraction; Titanium alloy; Biocompatibility; Borate bonding agents; Chemical durability; Metal-porcelain bond strength
• ISSN: 0928-4931; 1873-0191
• DOI: 10.1016/j.msec.2018.04.078

The purpose of this study was to investigate the properties of the borate bonding agents (BBAS) including chemical durability, biocompatibility and bonding characteristics of porcelain to Ti6Al4V. The bond strength was performed by the three-point bending test. And the chemical durability and ion release of BBAS were tested by chemical soaking and inductively coupled plasma optical emission spectrometry (ICP-OES), respectively. Moreover, cytotoxicity was evaluated by cell viability assay and cell adhesion using human osteosarcoma cells (MG-63) and cell counter kit-8 (CCK-8) assay. To investigate the influences of composition and microstructure changes on all the properties mentioned above, the 11B and 27Al spectra and infrared spectra of BBAS were measured by solid-state nuclear magnetic resonance (SSNMR) and Fourier transform infrared spectroscopy (FTIR), respectively. Combined with all these properties of BBAS, the optimal addition proportion of Al2O3 into BBAS is 20 mol%. The relative contents of [BO3], [BO4], [AlO4], [AlO5] and [AlO6] have great influences on these properties of BBAS. BBAS, possessing excellent chemical durability, good biocompatibility and low ion release and being an effective way to improve the Ti6Al4V-porcelain bond strength, have significant clinical potentials in porcelain fused to metal restorations. [Display omitted] •More Al2O3 addition into borate bonding agents is to adjust thermal properties.•Composition change of agents has greatly affected Ti6Al4V-porcelain bond strength.•Chemical durability and ion release are closely related to biocompatibility.•SSNMR and FTIR spectra are used for explaining the properties changes.