Short communication: Effect of 3 phytoceutical products on elimination of bacteria in experimentally induced Streptococcus uberis clinical mastitis

• Published in: Journal of dairy science Vol. 101; no. 11; pp. 10409 - 10413
• Main Authors: Mullen, K.A.E., Lyman, R.L., Washburn, S.P., Baynes, R.E., Anderson, K.L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2018
• Subjects: Animals; Anti-Bacterial Agents - pharmacology; Cattle; Female; Lactation; Mammary Glands, Animal - drug effects; Mammary Glands, Animal - microbiology; mastitis; Mastitis, Bovine - drug therapy; Mastitis, Bovine - microbiology; Milk - drug effects; Milk - microbiology; phytoceutical; Plant Preparations - pharmacology; Random Allocation; Streptococcal Infections - drug therapy; Streptococcal Infections - microbiology; Streptococcal Infections - veterinary; Streptococcus - drug effects; Streptococcus uberis; mastitis; phytoceutical; Streptococcus uberis
• ISSN: 0022-0302; 1525-3198
• DOI: 10.3168/jds.2017-14279

Our objective was to assess the ability of 3 herbal products to eliminate experimentally induced Streptococcus uberis mastitis. These herbal products, also known as phytoceuticals, are used in organically managed dairy cattle to maintain or promote udder health. The products tested were an intramammary product, a topical product, and a product applied to the vulvar area. These products are not approved by the US Food and Drug Administration for treatment of mastitis but they are sold to enhance milk quality or for maintenance or improvement of udder health. Each of the products contains at least one component shown to have antibacterial activity. In this study, we successfully challenge-inoculated 25 lactating dairy cows maintained under organic conditions with an isolate of S. uberis. All challenged cows were positive for S. uberis by milk culture after challenge. When cows met predefined criteria indicating the presence of clinical mastitis, treatment with 1 of the 3 products was initiated based upon a predetermined random allocation. Culture of aseptically collected quarter milk samples was performed before, during, and following challenge with S. uberis. Eight, 8, and 9 cows received the intravulvar, intramammary, and topical treatments, respectively. Milk from all cows that were treated with phytoceuticals were culture-positive for S. uberis at every time point following treatment through 168 h following the last phytoceutical treatment. Based upon the presence of clinical signs and for humane reasons, 2 intravulvar-treated cows, 1 topical-treated, and 4 intramammary-treated cows received intramammary antibiotic therapy. We concluded that the phytoceuticals tested, as dosed and used in this trial, did not produce bacterial cures in S. uberis-induced mastitis.