SIMULATION STUDY TO COMPARE THE RELATIONSHIP BETWEEN THE BLAST-INDUCED OBJECTIVE INDICES AND THE SURVIVAL RATE OF SUBJECTS WITH PRIMARY BLAST LUNG INJURY

When an injury due to blast overpressure (BOP) is generated, it is important to estimate the severity of the injury using information about the blast conditions and to supply proper treatments according to the degree of the damage. However, there have been no investigations that have tried to verify...

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Published inJournal of mechanics in medicine and biology Vol. 15; no. 4; pp. 1550043 - 1-1550043-15
Main Authors PARK, YOUNG MIN, NAM, KYOUNG WON, AHN, JONG HOON, JANG, DONG PYO, KIM, IN YOUNG
Format Journal Article
LanguageEnglish
Published Singapore World Scientific Publishing Company 01.08.2015
World Scientific Publishing Co. Pte., Ltd
Subjects
Computer simulation
Correlation analysis
Damage
Finite element method
Graphs
Injuries
Lungs
Overpressure
Patients
Strain rate
Survival
Thorax
VACC–VLUNG ratio graphs
finite element method
Primary blast injury
lung injury
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Summary:When an injury due to blast overpressure (BOP) is generated, it is important to estimate the severity of the injury using information about the blast conditions and to supply proper treatments according to the degree of the damage. However, there have been no investigations that have tried to verify the relationship between the blast-related objective indices and the degree of blast-induced injury. In this study, the correlations between the survival rate of the subjects with BOP-induced lung damage and each of four blast-induced indices, first principal strain, first principal strain rate, first principal stress and pulmonary inner pressure, were investigated using a simplified thorax model by introducing the concept of the VACC–VLUNG ratio graph which represents the volume ratio between the seriously-damaged meshes and the overall meshes of the thorax model in respect to each index. Experimental results demonstrated that the decay parameters of the sigmoidal curve-fitted graphs of the first principal stress are the most effective of the analyzed indices for the estimation of the survival rate in patients with blast-induced lung damage. The results have a potential clinical application to improve the efficacy of treatment for blast injury patients.
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ISSN:0219-5194
1793-6810
DOI:10.1142/S0219519415500438