Association between the 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene and sudden sensorineural hearing loss in Caucasian population: a meta-analysis

• Published in: European archives of oto-rhino-laryngology Vol. 278; no. 7; pp. 2203 - 2208
• Main Authors: Wei, Zhenxing, Chang, Kunpeng, Fan, Chongsheng
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2021
• Subjects: Genetic Predisposition to Disease; Genotype; Head and Neck Surgery; Hearing Loss, Sensorineural - genetics; Humans; Medicine; Medicine & Public Health; Neurosurgery; Odds Ratio; Otorhinolaryngology; Plasminogen Activator Inhibitor 1 - genetics; Polymorphism, Genetic; Review Article; Risk Factors; Plasminogen activator inhibitor-1 (PAI-1); Sudden sensorineural hearing loss; 4G/5G polymorphism; Caucasian population; Meta-analysis

Purpose To clarify the association between the 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) and sudden sensorineural hearing loss (SSNHL). Methods A systematic literature search of related studies up to August 30, 2019 in the PubMed and Embase databases was performed, and the resu...