Immunization with messenger RNA vaccines against COVID-19 in adolescents with a history of multisystem inflammatory syndrome: a case series

In most cases, children with SARS-CoV-2 have a mild infection. However, very rarely, some children may develop a severe disease called multisystem inflammatory syndrome in children temporally associated with COVID-19 (MIS-C). Given its recent emergence, some aspects of its pathophysiology are still...

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Published inArchivos argentinos de pediatría Vol. 121; no. 3; p. e202202757
Main Authors Curtti, Tamara, Agrimbau Vázquez, Jorge, Yori, Silvana, Kantarovsky, Ana, Torolla, José, Di Santo, Marisa, Hammermüller, Erica, Urrutia, Luis, Parra, Adriana
Format Journal Article
LanguageEnglish
Published Argentina 01.06.2023
Subjects
Adolescent
COVID-19 - complications
COVID-19 - prevention & control
COVID-19 Vaccines - administration & dosage
Humans
mRNA Vaccines - administration & dosage
SARS-CoV-2
Vaccination
COVID-19
COVID-19 vaccines
mRNA vaccines
SARS-CoV-2
multisystem inflammatory syndrome in children associatedwith COVID-19
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Summary:In most cases, children with SARS-CoV-2 have a mild infection. However, very rarely, some children may develop a severe disease called multisystem inflammatory syndrome in children temporally associated with COVID-19 (MIS-C). Given its recent emergence, some aspects of its pathophysiology are still unknown. The possibility of recurrence in case of reinfection or SARS-CoV-2 vaccination are new questions we are facing. Here we report a case series of 4 adolescent patients who developed MIS-C and, months later, received the SARS-CoV-2 vaccine with messenger RNA (mRNA) platforms without disease recurrence or cardiac adverse events.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0325-0075
1668-3501
DOI:10.5546/aap.2022-02757.eng