A NOVEL ROUTE TO 2-ALKOXY ARYLOXYTHIOPHENES VIA SIMMONS-SMITH REACTION ON ACYLKETENE O,S-ACETALS

A novel route to 2-alkoxy/aryloxy-4-arylthiophenes 4a-k and the corresponding 3,4-annulated thiophene 7 has been developed by subjecting the respective acylketene O,S-acetals 1a-k and 6 to Simmons-Smith reaction conditions (zinc-copper/diiodomethane).

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Bibliographic Details
Published inSynthesis (Stuttgart) no. 10; pp. 959 - 960
Main Authors BHAT, L, ILA, H, JUNJAPPA, H
Format Journal Article
LanguageEnglish
Published STUTTGART Thieme Medical Publishers 1993
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:A novel route to 2-alkoxy/aryloxy-4-arylthiophenes 4a-k and the corresponding 3,4-annulated thiophene 7 has been developed by subjecting the respective acylketene O,S-acetals 1a-k and 6 to Simmons-Smith reaction conditions (zinc-copper/diiodomethane).
ISSN:0039-7881
DOI:10.1055/s-1993-25978